United Launch Alliance’s 50th mission for the U.S. Air Force lifted off at 12:15 a.m. EDT (0415 GMT) Wednesday. An Atlas 5 rocket launched from Cape Canaveral with the Air Force’s fourth Advanced Extremely High Frequency communications satellite.

Liftoff from Space Launch Complex 41 at Cape Canaveral Space Force Station occurred at 3:28 a.m. EST (0828 UTC), as the RD-180 engine on the booster roared to lift alongside five solid rocket boosters.

A Dragon supply ship owned and operated by SpaceX departed the International Space Station early Monday and returned to Earth for a predawn splashdown in the Pacific Ocean southwest of Los Angeles with scientific specimens and other equipment. Astronaut Jack Fischer released the Dragon cargo capsule from the station’s robotic arm at 2:41 a.m. EDT (0641 GMT), and splashdown occurred around 8:12 a.m. EDT (1212 GMT).