A Russian Progress cargo spacecraft laden with 5,300 pounds of fuel and supplies blasted off from the Baikonur Cosmodrome in Kazakhstan on Saturday, riding a Soyuz rocket smoothly into orbit on the first of two resupply launches heading for the International Space Station in the next two days.

SpaceX test-fired a Falcon 9 rocket Wednesday afternoon at NASA’s Kennedy Space Center in Florida, clearing a major hurdle before it launches Saturday night — weather permitting — with a four-person crew heading for the International Space Station.

A SpaceX Dragon cargo capsule concluded a 30-day stay at the International Space Station Tuesday with an automated departure from the orbiting research outpost at 5:05 a.m. EST (1005 GMT) Tuesday. The Dragon’s release from the robotic arm set the stage for a scorching re-entry and splashdown in the Pacific Ocean southwest of Los Angeles at around 10:41 a.m. EST (1541 GMT).