VIDEO: Expedition 42-43 mission preview

Europe’s fifth and final Automated Transfer Vehicle departed the International Space Station for the last time Saturday, closing out one of the European Space Agency’s flagship programs as the bus-sized spaceship heads for a destructive re-entry Sunday.

The Russian Progress 58P cargo freighter launches and six hours later docks to the International Space Station.

Two Russian cosmonauts and a U.S. Navy test pilot will buckle into custom-molded seats inside a Soyuz spaceship Wednesday, undock from the International Space Station and head for a parachute-assisted landing in Kazakhstan to close out a 167-day space voyage.