After a 22-day stay at the International Space Station, an Orbital ATK Cygnus supply ship is set for departure Wednesday en route to a higher orbit for release of 14 CubeSats for commercial weather monitoring and technology demonstrations. The robotic Cygnus spacecraft is scheduled for release from the station’s robotic arm at 8:10 a.m. EST (1310 GMT) Wednesday.

Packed with nearly 3 tons of rocket fuel, water, oxygen and crew provisions, the Russian Progress MS-12 supply ship and its Soyuz booster arrived at a launch pad Sunday at the Baikonur Cosmodrome in Kazakhstan, moving a step closer to liftoff Wednesday on a fast-track three-hour flight to the International Space Station.

The International Space Station received more than 2.5 tons of fresh supplies and experiments Sunday with the arrival of a commercial Cygnus cargo vessel after an automated laser-guided rendezvous.