The space shuttle can reach a runway or a lower-than-planned orbit in the event of a single main engine failure at any point after liftoff. For Endeavour's flight, an engine failure in the first two minutes and 37 seconds of flight would result in a return-to-launch-site - RTLS - abort. Between approximately 2:38 and 4:58, an engine failure would result in a trans-Atlantic landing - TAL - in either Spain or Africa. After four minutes and 58 seconds, Endeavour would be able to abort into a safe but lower-than-planned orbit, or ATO. The only in-flight abort in shuttle history was an ATO on July 29, 1985, when Challenger's center engine shut down five minutes and 45 seconds into the 19th shuttle mission (STS-51F).

NOTE: Inertial velocity includes contribution from Earth's rotation.
 
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